Wales will be the first UK nation to scrap travel restrictions within country boundaries from Saturday, since lockdowns were re-imposed in winter.
This means that “stay-local” rules will lift in Wales and unrestricted travel within its borders will be allowed.
Self-contained tourist accommodation – including many hotels and cottages – will also be able to open on Saturday.
But non-essential travel to and from other UK nations will be banned for at least two weeks.
The move by the Welsh government will also see rules on the number of people who can meet outdoors – including in private gardens – eased.
Six people from two households will be able to meet up, an increase from the current four-person limit.
Organized outdoor activities and sports for under-18s can resume, and libraries and archives will be able to reopen their doors.
First Minister Mark Drakeford said the “public health position remains stable” and there is “headroom” to make changes.
“These further relaxations are part of our careful and phased approach to unlocking the restrictions and enabling people and businesses to resume their activities in the safest possible way,” he said.
Rules will also allow a limited opening of outdoors areas of some historic places and gardens.